解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::This study investigated whether neural mechanisms of self-face recognition are modulated by attention by recording event-related brain potentials associated with self-face recognition. Participants identified head orientations of self-faces and familiar or unfamiliar other faces presented briefly at the center of the ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000203357.65190.61
更新日期:2006-03-20 00:00:00
abstract::Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using the streptozotocin-induced diabetic rat model we document for the first time the over-expression of a mitochondrial specific stress protein (chaperonin 60) in ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000201503.15632.06
更新日期:2006-02-27 00:00:00
abstract::Mesencephalic astrocyte-derived neurotrophic factor (MANF) - one of a new class of astrocyte-derived human proteins--selectively promotes the survival of dopamine neurons of the ventral midbrain. Using the whole-cell clamp technique, we looked for acute effects of MANF on gamma-aminobutyric acid type A (GABAA) recepto...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000201504.23255.bc
更新日期:2006-02-27 00:00:00
abstract::The effects of high frequency repetitive transcranial magnetic stimulation on sensory perception and the pain tolerance thresholds were investigated applying both motor cortex stimulation and medial frontal cortex stimulation in normal study participants. Both the sensory perception and pain tolerance thresholds were ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000198438.37012.d6
更新日期:2006-02-06 00:00:00
abstract::A novel allograft paradigm was used to test whether adult mammalian central axons regenerate within a peripheral nerve environment containing intact sensory axons. Retinal ganglion cell axon regeneration was compared following anastomosis of dorsal root ganglia grafts or conventional peripheral nerve grafts to the adu...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000195668.07467.a8
更新日期:2006-02-06 00:00:00
abstract::Functional neuroimaging studies of handedness have traditionally focused on exploring regionally activated discrepancies, yet little is known regarding the effect of handedness on functional connections of brain regions. Here, we reported the relationship between cerebellar functional connectivity patterns and handedn...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000192737.92911.a4
更新日期:2006-01-23 00:00:00
abstract::Damage to central nervous system white matter is observed following hypoglycemia, raising the possibility that hypoglycemia influences oligodendrocytes and myelination. To examine effects of hypoglycemia on oligodendrocytes and myelin formation, we studied cultured oligodendrocyte precursor cells and cerebellar slice ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000192733.00535.b6
更新日期:2006-01-23 00:00:00
abstract::In the water-maze test, the linoleic acid derivative, 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) (1 mg/kg, intraperitoneally), significantly shortened the prolonged latency for accelerated-senescence-prone mice 8 (SAMP8), reaching a level similar to the latency for accelerated-senescence-res...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000194388.12408.0a
更新日期:2006-01-23 00:00:00
abstract::Experiments using chimeric stimuli have shown that the right hemisphere is more influential in processing facial information. Here, again, we found clear evidence that study participants used the information from the left side of the face to inform their gender decisions when chimeric male/female, female/male stimuli ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200512190-00004
更新日期:2005-12-19 00:00:00
abstract::We have previously reported that the developmental exposure of rats to altered gravity (1.65 g) from gestational day 8 to postnatal day 21 impacts motor functions and cerebellar structure. The present study examined whether the decrease in cerebellar mass accompanied by impaired performance on a rotorod in hypergravit...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200512190-00014
更新日期:2005-12-19 00:00:00
abstract::Recently, it has been shown that visual perception can be radically altered by signals of other modalities. For example, when a single flash is accompanied by multiple auditory beeps, it is often perceived as multiple flashes. This effect is known as the sound-induced flash illusion. In order to investigate the princi...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000187634.68504.bb
更新日期:2005-11-28 00:00:00
abstract::Previous research has suggested that exposure to radiofrequency electromagnetic fields increases electroencephalogram spectral power in non-rapid eye movement sleep. Other sleep parameters have also been affected following exposure. We examined whether aspects of sleep architecture show sensitivity to electromagnetic ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000186593.79705.3c
更新日期:2005-11-28 00:00:00
abstract::Previous literature shows that feature binding processes elicit fronto-hippocampal areas. The time course of this process, however, remains unknown. This is the first study that investigates feature binding using magnetoencephalography. Synthetic aperture magnetometry analysis was used to localize sources of increased...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000185020.75057.19
更新日期:2005-11-07 00:00:00
abstract::The present study used the N400, an electrophysiological correlate of semantic processing, to investigate 19- and 24-month-old children's ability to integrate the meaning of words in a sentential context. Children listened passively to semantically appropriate sentences and to sentences in which the object noun violat...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000185013.98821.62
更新日期:2005-11-07 00:00:00
abstract::Although decision-making is typically seen as a rational process, emotions play a role in tasks that include unfairness. Recently, activation in the right dorsolateral prefrontal cortex during offers experienced as unfair in the Ultimatum Game was suggested to subserve goal maintenance in this task. This is restricted...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000183907.08149.14
更新日期:2005-11-07 00:00:00
abstract::For many diseases and injuries of the central nervous system, transplantation of neural progenitor cells is being evaluated as a possible treatment option. Although local, intravenous and subarachnoid injections have been reported as administration methods of neural progenitor cells, each of these methods has limitati...
journal_title:Neuroreport
pub_type: 杂志文章
doi:
更新日期:2005-10-17 00:00:00
abstract::Activation of mu-opioid receptors is critical to steroid regulation of female sexual behavior, lordosis, in rodents. Estrogen treatment activates mu-opioid receptors in the medial preoptic area inhibiting lordosis, but ultimately appears important for progesterone facilitation of lordosis. We investigated the role of ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000181585.49130.93
更新日期:2005-10-17 00:00:00
abstract::In several central nervous system neuronal populations, axotomy triggers the upregulation of regeneration-associated genes such as c-Jun, which determines neurons ability to regenerate axon in a growth-permissive environment. We analyzed the expression of c-Jun in rat ventral medullary neurons after cervical hemisecti...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000179075.32035.0f
更新日期:2005-09-28 00:00:00
abstract::The effects of copper on voltage-gated A-type potassium currents were investigated in acutely dissociated rat hippocampal CA1 neurons using the whole-cell patch-clamp technique. Extracellular application of various concentrations of copper (1-1000 microM) reversibly reduced the amplitude of voltage-gated A-type potass...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000181578.72894.b9
更新日期:2005-09-28 00:00:00
abstract::With increasing age, the electrophysiological event-related potentials P3a/P3b tend to get a more frontal maximum. The cognitive significance of this so-called frontal shift is not known, but hypotheses have focused on changes in the integrity of the frontal lobes. The aim of the present study was to test how the thic...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000177011.44602.17
更新日期:2005-09-08 00:00:00
abstract::Recent studies have discussed the role of the cerebellum in not only motor but also cognitive functions, and in particular, fronto-executive operations. Similar to a previous study on hemineglect patients, we recorded eye movements during a visual search task to investigate patients with isolated infarction of the cer...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000177015.75096.b6
更新日期:2005-09-08 00:00:00
abstract::Recently, we have demonstrated that bone marrow stem cells can differentiate into retinal nerve cells. In the present study, we show a new and efficient strategy for transplanting bone marrow stem cells into the retina. When bone marrow stem cells were injected into the vitreous cavity of untreated eyes, only very few...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000176517.96475.18
更新日期:2005-08-22 00:00:00
abstract::Hypoxic-ischemic represents a common cause of damage to the prenatal brain and can co-occur with prematurity. Prematurity is associated with emergent language impairments, and it has been suggested that rapid auditory processing deficits play a causal role in language difficulties. We previously demonstrated rapid aud...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175613.16183.6c
更新日期:2005-08-22 00:00:00
abstract::Using quantitative autoradiography, the present study examined ionotropic glutamatergic receptor binding sites using [3H]dizocilpine, [3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate, and [3H]kainate in the posterior cingulate cortex of schizophrenia patients and matched controls. We found a significant increa...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000174056.11403.71
更新日期:2005-08-22 00:00:00
abstract::Autophosphorylation of the alpha-isoform of Ca2+/calmodulin-dependent kinase II switches the kinase into an autonomous activity mode. This molecular switch is important for hippocampal long-term memory formation, which requires de novo gene transcription and protein synthesis. Here, we have studied whether auto-phosph...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/01.wnr.0000175244.51084.bb
更新日期:2005-08-22 00:00:00
abstract::Selective degeneration of hypothalamic orexin neurons, a hallmark of pathology in narcolepsy patients, is in part reproduced in hypothalamic slice cultures by application of an endogenous excitotoxin quinolinic acid. Depolarized membrane potential may be responsible for the vulnerability of orexin neurons to excitotox...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200508010-00005
更新日期:2005-08-01 00:00:00
abstract::Poly(ADP-ribose) polymerase-1 consumes NAD to catalyze poly(ADP-ribosyl)ation of target proteins, which modulates various biological functions. However, excessive poly(ADP-ribose) polymerase-1 activation mediates oxidative cell death. Our recent studies have indicated that NAD can enter into astrocytes to prevent poly...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200508010-00015
更新日期:2005-08-01 00:00:00
abstract::The perifornical-lateral hypothalamic area is implicated in regulating waking and paradoxical sleep. The blockade of GABAA receptors by iontophoretic applications of bicuculline (or gabazine) into the perifornical-lateral hypothalamic area induced a continuous quiet waking state associated to a robust muscle tone in h...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200507130-00008
更新日期:2005-07-13 00:00:00
abstract::Substantial evidence suggests a negative association between cigarette smoking and the incidence and severity of ulcerative colitis, a common human inflammatory bowel disease. Nicotine has been implicated in this association. The detection of nicotinic acetylcholine receptors in colonic epithelium, the primary tissue ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200507130-00018
更新日期:2005-07-13 00:00:00
abstract::24S-hydroxycholesterol, the primary oxidation product of cholesterol in the brain, plays a key role in cholesterol elimination and homeostasis. While the concentration of this neurotoxic oxysterol decreases with age, 24S-hydroxycholesterol is elevated in Alzheimer's disease. In this study, we examined the effects of 2...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200506210-00007
更新日期:2005-06-21 00:00:00
abstract::Pyramidal cells were injected intracellularly in fixed, flat-mounted cortical slices taken from the first and fourth visual areas (V1 and V4, respectively) and cytoarchitectonic areas TEO and TE of two age and gender-matched vervet monkeys and the size, branching complexity and spine density of their basal dendritic t...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200506210-00017
更新日期:2005-06-21 00:00:00
abstract::Using functional magnetic resonance imaging during word generation and spatial judgement (Landmark task), we investigated how hemispheric specializations for language and spatial processing interact in healthy individuals. We found individuals with atypical, right-hemispheric dominance for language to have more bilate...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200506210-00027
更新日期:2005-06-21 00:00:00
abstract::This study examined the potential of embryonic stem cell-derived neurons as transplants for cell therapy for the primary loss of spiral ganglion neurons. To assess the ability of embryonic stem cell-derived neurons for innervation into auditory epithelia, they were cocultured with auditory epithelium explants of mice ...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200505310-00001
更新日期:2005-05-31 00:00:00
abstract::Neural progenitor/stem cells reside in the subventricular zone and dentate gyrus of the adult rat brain, which proliferate in response to several growth factors. Here we show that the neurospheres generated from the adult dentate gyrus and subventricular zone proliferate in vitro in response to fibroblast growth facto...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200505310-00011
更新日期:2005-05-31 00:00:00
abstract::The present study was performed to examine how intention to learn and explicit knowledge in sequence learning are reflected in event-related potentials. Participants responded to numerals presented in a repeating order, which were replaced infrequently by deviant numerals. The participants were given incidental or int...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200505120-00010
更新日期:2005-05-12 00:00:00
abstract::Inhibition, the process that overrides and reverses the execution of a thought, action, or emotion, is important in daily life. Sixteen healthy volunteers performed a parametrically modulated motor inhibition task during functional magnetic resonance imaging. Two results were observed: (1) increased error-related ante...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200505120-00020
更新日期:2005-05-12 00:00:00
abstract::Amyotrophic lateral sclerosis is a devastating motor neuron disorder. Traditionally regarded as a 'neuron only' disease, recent evidence suggested that other cells contribute critically to the pathogenesis. This review provides a short synopsis of the role neuroinflammation and microglial cells play in the disease and...
journal_title:Neuroreport
pub_type: 杂志文章,评审
doi:10.1097/00001756-200504250-00001
更新日期:2005-04-25 00:00:00
abstract::The H-Tx rat is a polygenic inherited model of hydrocephalus. In order to identify disease-specific biomarkers associated with congenital hydrocephalus, comparative proteomic analysis was used to screen cerebellum proteins in H-Tx rats at 1 day after birth. Seven proteins showed significant changes in hydrocephalic H-...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200504250-00011
更新日期:2005-04-25 00:00:00
abstract::Using functional magnetic resonance imaging, we explored the role of semantics in mediating orthographic-to-phonological processing in reading aloud, focusing on the interaction of imageability with spelling-to-sound consistency for low-frequency words. Behaviorally, high-imageable words attenuate the standard latency...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200504250-00021
更新日期:2005-04-25 00:00:00
abstract::Calsenilin, a multifunctional Ca2+-binding protein, has been identified as an Alzheimer's disease-associated presenilin interactor. Here, we investigated the histochemical localization of calsenilin and its expression levels in the brains of sporadic Alzheimer's disease. Both messenger RNA and protein expression of ca...
journal_title:Neuroreport
pub_type: 杂志文章
doi:10.1097/00001756-200504040-00007
更新日期:2005-04-04 00:00:00